Qlopedia

Protein database website, sequences, annotations, proteomes, taxonomy, API

Website

UniProt

UniProt is a protein information website and database resource for searching protein sequences, annotations, functions, taxonomy, proteomes, evidence, cross-references, and API-accessible biological data.

Official site
uniprot.org is the main public website for UniProt.
Product focus
UniProt focuses on protein sequences, functional annotations, taxonomy, proteomes, reviewed and unreviewed records, cross-references, and APIs.
Consortium
UniProt is a collaboration involving EMBL-EBI, SIB Swiss Institute of Bioinformatics, and the Protein Information Resource.
The UniProt logo.View logo on Wikimedia Commons

What UniProt is

UniProt is a protein information website at uniprot.org that provides protein sequence and functional information. Its public pages and APIs help researchers, students, curators, and software tools search protein records, annotations, evidence, taxonomy, proteomes, and cross-references.

Protein information resource

UniProt's stated mission is to provide the scientific community with a comprehensive, high-quality, freely accessible resource of protein sequence and functional information. The resource is maintained by a consortium involving EMBL-EBI, SIB Swiss Institute of Bioinformatics, and the Protein Information Resource.

UniProtKB

The UniProt Knowledgebase, or UniProtKB, is the central hub for protein sequence and annotation data. Entries include core information such as amino acid sequence, protein name or description, organism, taxonomy, citations, and links to related scientific databases.

Reviewed and unreviewed entries

UniProtKB includes reviewed Swiss-Prot records and unreviewed TrEMBL records. The distinction matters: reviewed entries have manual curation, while unreviewed records are computationally analyzed and await full manual annotation.

Annotations and evidence

Protein records can include functional descriptions, domains, active sites, variants, post-translational modifications, subcellular location, protein families, sequence features, evidence tags, and cross-references. These annotations help users move from a sequence to biological meaning, but each claim still needs context.

Clusters and archive records

UniProt also provides resources such as UniRef clusters and UniParc archive records. These help reduce redundancy, track protein sequence history, and support large-scale analyses where users need more than one curated entry page.

API access

UniProt supports programmatic access through APIs and documentation. Developers can retrieve records, search UniProtKB, integrate identifiers into pipelines, and connect protein information with genomics, proteomics, structural biology, medicine, and chemistry workflows.

Why it matters

UniProt matters because proteins are central to cells, organisms, disease, biotechnology, and evolution. A shared protein information website helps researchers connect sequences with function, evidence, literature, organisms, variants, and related databases.

WHOIS domain data

Data pulled: June 1, 2026View current WHOIS record

Domain
uniprot.org
IP address
193.62.193.81
Registrar
GoDaddy.com, LLC
WHOIS server
whois.godaddy.com
Referral URL
http://www.whois.godaddy.com
Created
February 26, 2002
Updated
January 31, 2026
Expires
February 26, 2031
Nameservers
ns29.domaincontrol.com (97.74.104.15); ns30.domaincontrol.com (173.201.72.15)
Domain status
clientDeleteProhibited; clientRenewProhibited; clientTransferProhibited; clientUpdateProhibited
DNSSEC
unsigned